Compressible flows with a suspended dispersed phase are ubiquitous both in nature and in engineering applications. The topic of this thesis is the development of an Euler-Lagrange method suitable for the simulation of compressible dispersed high-Reynolds number flow on massively parallel systems. The employed high-order accurate flow solver utilizes the highly efficient Discontinuous Galerkin Spectral Element Method to solve the unsteady Navier-Stokes equations for the continuous phase. The implementation of the dispersed phase ensures efficient parallelization and enables rapid in-memory load balancing. Relative motion between the blade rows is captured with a conservative, high-order accurate sliding mesh approach for both the continuous and the dispersed phase. The scaling capabilities of the method are demonstrated on modern high performance computing systems. The developed framework is applied to two dispersed multiscale turbomachinery flow applications, leveraging the scale-resolving capabilities for time-accurate analysis of the unsteady particle dynamics. The particle transport in the presence of a bluff body with a wall junction is analyzed using a finite wall-mounted cylinder setup. The influences of the wall boundary layer and the free end of the cylinder on the dispersed phase are quantified. The impact of deterministic fluctuations imposed by a cylindrical wake generator on the particle-laden flow is studied in a transonic compressor cascade. Spatio-temporal analysis is performed on both the continuous and the dispersed field. The efficacy of the wake generator in producing a realistic particle field at the cascade entry is investigated by comparison against a setup with undisturbed inflow.weiterlesen