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Base Editors

Methods and Protocols

Produktform: E-Buch Text Elektronisches Buch in proprietärem

This volume explores base editors (BEs), an invaluable CRISPR-based genome editing tool with a wide variety of versatile applications. Beginning with an overview of BEs, their diverse variants, and computational tools, the book continues with experimental applications of BEs for disease modeling in mammalian cells and generating mutagenic mice, therapeutic base editing strategies, which covers delivery methods of BE-encoded DNA plasmids, mRNAs, or ribonucleoproteins through viruses or non-viral lipid nanoparticles, and lastly, the use of BEs in plants and bacteria. Written for the highly successful series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, serves as an ideal guide for researchers looking to use base editors to continue their studies in an array of fields.weiterlesen

Dieser Artikel gehört zu den folgenden Serien

Elektronisches Format: PDF

Sprache(n): Englisch

ISBN: 978-1-07-162879-9 / 978-1071628799 / 9781071628799

Verlag: Springer US

Erscheinungsdatum: 02.01.2023

Seiten: 235

Herausgegeben von Sangsu Bae, Beomjong Song

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