This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play a crucial role in transepithelial ion and fluid transport across all epithelia and their contribution to maintaining homeostasis. Readers will be introduced to the fundamentals of ion transport in terms of function, modelling, regulation, structure and pharmacology. This is the first of three volumes highlighting the importance of ion channels and transporters in the  basic physiology and pathophysiology of human diseases.The focus of the first volume is on measurement techniques for epithelial transport and the mathematical modelling of these processes. Accordingly, the authors explain e.g. the fundamentals of bicarbonate secretion, volume regulation, protein folding of ion channels and transporters, and fundamentals of epithelial sodium, potassium. and chloride transport, and microRNA regulation of epithelial channels and  transporters. Given its scope, the book offers a valuable resource for physiology students, scientists and clinicians alike. weiterlesen