The presented retrospective survival analysis, aims to examine patient-specific factors potentially influencing implant-prosthetic treatment. Thus, the results can give recommendations for this treatment option. During the observation period from 2003 to 2023, in total 469 patients with overall 1627 implants were analyzed by use of the MZD program and finally included into the evaluation. Statistical analysis was conducted using Kaplan-Meier method for pair-wise comparison and Cox regression for multifactorial analysis. Regarding implant-supported dental prostheses (n = 1665), a mean survival time of 14.64 ± 0.24 years and a risk of functional loss of 7.2 % were recorded. The most common complication (82 cases) was the explantation of an implant leading to con-current loss of function of the implant-supported dental prostheses. The cumulative 5-, 10-, and 15-year survival rates for all implant-supported dental prostheses were 93.1 %, 84.3 %, and 67.6 %, respectively. For the included implants (n = 1627), a mean survival time of 15.98 ± 0.20 years was calculated. Approximately 5.0 % had to be explanted, with more than half of the cas-es due to periimplantitis. After an observation period of 5, 10, and 15 years, the sur-vival rates were 96.6 %, 89.4 %, and 76.3 %, respectively. Furthermore, the patient-specific factors "jaw," "splinting," and "tumor disease" had a significant influence (p 0.05) on the survival rate of the implants regarding the splinting of the prosthetic restoration. Nevertheless, both implant-supported dental prostheses and implants showed highly significant lower survival probabilities (p weiterlesen