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Camptothecins in Cancer Therapy

Produktform: Buch / Einband - fest (Hardcover)

A critical review our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer potential of camptothecins, and the question of camptothecin resistance.weiterlesen

Dieser Artikel gehört zu den folgenden Serien

Sprache(n): Englisch

ISBN: 978-1-58829-027-4 / 978-1588290274 / 9781588290274

Verlag: Humana Press

Erscheinungsdatum: 01.02.2005

Seiten: 460

Auflage: 1

Herausgegeben von Val R. Adams

213,99 € inkl. MwSt.
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