This book constitutes the refereed proceedings of the 33rd International Workshop on Combinatorial Algorithms, IWOCA 2022, which took place as a hybrid event in Trier, Germany, during June 7-9, 2022.The 35 papers presented in these proceedings were carefully reviewed and selected from 86 submissions. They deal with diverse topics related to combinatorial algorithms, such as algorithms and data structures; algorithmic and combinatorical aspects of cryptography and information security; algorithmic game theory and complexity of games; approximation algorithms; complexity theory; combinatorics and graph theory; combinatorial generation, enumeration and counting; combinatorial optimization; combinatorics of words; computational biology; computational geometry; decompositions and combinatorial designs; distributed and network algorithms; experimental combinatorics; fine-grained complexity; graph algorithms and modelling with graphs; graph drawing and graph labelling; network theory and temporal graphs; quantum computing and algorithms for quantum computers; online algorithms; parameterized and exact algorithms; probabilistic andrandomized algorithms; and streaming algorithms. weiterlesen