Presents a historical overview of eukaryotic DNA replication by one of the legendary scientists in the field Reviews comprehensive compilation of the newest information on DNA replication Approaches issues related to DNA replication from various points of view Emphasizes the latest results on mechanistic and structural aspects of DNA replication Features the most recent development on the genome-wide view of where and when DNA replication starts and stops, and how those profiles are correlated with other genomic signatures Provides a novel concept for the highly adaptive and plastic mode of eukaryotic DNA replicationweiterlesen