This book focuses on recent developments in docking simulations for target proteins with chapters on specific techniques or applications for docking simulations, including the major docking programs. Additionally, the volume explores the scoring functions developed for the analysis of docking results and to predict ligand-binding affinity as well as the importance of docking simulations for the initial stages of drug discovery. Written for the highly successful series, this collection presents the kind of detail and key implementation advice to ensure successful results. Authoritative and practical, aims to serve those interested in molecular docking simulation and also in the application of these methodologies for drug discovery.weiterlesen