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Formulating Poorly Water Soluble Drugs

Produktform: Buch / Einband - fest (Hardcover)

The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.weiterlesen

Dieser Artikel gehört zu den folgenden Serien

Sprache(n): Englisch

ISBN: 978-3-030-88718-6 / 978-3030887186 / 9783030887186

Verlag: Springer International Publishing

Erscheinungsdatum: 20.05.2022

Seiten: 693

Auflage: 3

Herausgegeben von Robert O. Williams III, Dave A. Miller, Daniel A. Davis Jr.

246,09 € inkl. MwSt.
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