This book discusses the unique ion channels and transporters found within the epithelial tissues of various organs, including the kidney, intestine, pancreas and respiratory tract. Demonstrating the crucial role that each of these channels and transporters plays in transepithelial ion and fluid transport across all epithelia, as well as in maintaining homeostasis, it allows readers to gain an understanding of the fundamentals of ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. All three volumes highlight the importance of ion channels and transporters in basic physiology and pathophysiology of human diseases.This second volume focuses on a wide array of epithelial tissues and the use of organoids to study epithelial function. Furthermore, clinical research scientists from various fields provide a medical perspective on the ‘real’ physiology to ‘round out’ the reader’s journey from basic science to the laboratory bench and clinical management of molecular diseases, making this a must-read for students and scientists in the field of physiology, as well as for clinicians. weiterlesen