Frontmatter -- Preface -- Introduction -- Table of Contents -- I. Basic Problems of Normal Limb Development -- Developmental Control of Spatial Sequences of Structures / Meinhardt, Hans -- Antero-Posterior Positional Signalling in the Developing Chick Limb / Honig, Lawrence S. -- Morphological and Histochemical Aspects of the Subridge Mesoderm in Avian and Mammalian Limb Buds / Milaire, Jean -- Control by the Posterior Border of Cell Death Patterns in Limb Bud Development of Amniotes: Evidence from Experimental Amputations and from Mutants / Hinchliffe, J.R. -- Characterization of Embryonic Cholinesterase in the Chondrogenic Core of the Chick Limb Bud and Demonstration of a Specific Acetylcholine Receptor / Drews, Ulrich / Schröder, Christoph / Schmidt, Heinrich -- Limb Chondrogenesis: Interactions between Ectoderm and Mesoderm / Gumpel-Pinot, Madeleine -- Role of the Ectoderm in Limb Development of Normal and Mutant Mouse (Disorganization, Pupoid Foetus) and Fowl (Talpid3) Embryos / Ede, D.A. -- Origin, Distribution and Determination of Chick Limb Mesenchymal Cells / Christ, B. / Jacob, H.J. -- The Concept of a Myogenic Cell Line in Developing Avian Limb Buds / Kieny, Madeleine -- On the Formation of Muscular Pattern in the Chick Limb / Jacob, H.J. / Christ, B. -- Muscle Development during Normal and Disturbed Skelettogenesis / Bogusch, G. -- Developmental Properties of the Foot Integument in Avian Embryos / Sengel, P. -- The Contrast between Mouse and Ferret Limb Buds in Culture - Possible Advantages of Comparing Results from a Limb Culture System with Whole Embryo Explantation / Beck, F. / Gulamhusein, A.P. -- Transfilter Interaction of the Zone of Polarizing Activity with the Apical Ectodermal Ridge and the Distal Mesenchyme in the Chick Embryo Wing Bud in Ovo / Kaprio, Eero A. -- Simulation of Steps of Limb Skelettogenesis in Vitro / Merker, H.-J. / Zimmermann, B. / Barrach, H.-J. / Grundmann, K. / Ebel, H. -- Effects of Surface Coat Influencing Substances on the Limb Bud Blastema in Vitro / Zimmermann, Bernd -- Effects of Surface Coat Influencing Substances on the Limb Bud Blastema in Vitro Bernd Zimmermann / Herken, R. -- The Occurrence of Unilateral Abnormality of the Limb Induced by the Teratogen 6-Aminonicotinamide / Barrach, H.-J. / Dillmann, I. -- Ascorbic Acid Content of Limb Buds at Different Stages of Mammalian Embryonic Development / Blankenburg, Gudrun / Rautenberg, Margret / Neubert, Diether -- II. EXPERIMENTAL EMBRYOLOGY AND TERATOLOGY -- A. Experimental Embryology -- Abnormalities along the Proximo-Distal Axis of the Chick Wing Bud: The Effect of Surgical Intervention / Hornbruch, Amata -- The Effects of X-lrradiation on Limb Development / Summerbell, Dennis -- Effects of Matrix Influencing Substances on Chondrocyte in Monolayer Culture / Zimmermann, Bernd -- The Influence of Nerve Supply in Limb Development / McBride, W. G. / Stokes, P. A. / Vardy, P. H. -- Defective Innervation and Defective Limbs: Causes and Effects in the Developing Chick Wing / Lewis, Julian -- B. General Aspects of Teratology -- On the Problem of Phase Specificity in Limb Teratogenesis / Neubert, Diether / Dillmann, Imke -- The Problem of Growth Retardation / Leone, Vincenzo G. -- Bilaterally Symmetric and Asymmetric Realization of Limb Malformations / Kocherand, W. / Kocher-Becker, U. -- Immunofluorescent Microscopic Investigations of Intercellular Substances during Limb Development / Barrach, H.-J. / Grundmann, K. / Hinz, N. / Felies, A. -- An Analysis of the Asymmetric Response of the Developing Limb to Embryotoxic Agents / Skalko, Richard G. / Kwasigroch, Thomas E. -- Resistance of the Rat to Certain Specific Limb Teratogens / Tuchmann-Duplessis, H. -- Observations on Human Digits 'In Vitro' and its Possible Role in Evaluating Teratogens / Rajan, K. T. / Merker, H.-J. / Wilkins, M. -- The Effects of Sodium Salicylate, Cytosine Arabinoside, and Eserine Sulphate on Rat Limb Buds in Culture / Flint, O. P. -- C. Effects of Teratogenic Agents -- The Transplacental Effects of Vitamin D Metabolites and Corticosteroids on the Long Bones of Rat and Mice Fetuses / Ornoy, A. / Hirsch, B. E. / Zusman, I. / Atkin, I. -- The Effect of Cytosine-Arabinoside on Limb Morphogenesis in the Mouse / Rooze, M. A. -- Mechanisms of Limb Development Revealed by the Teratogenic Activity of Nicotinamide Analogues / McLachlan, John C. -- Analysis of Radiographs in Reproduction Toxicology by Means of Densitometry and Planimetry / Sterz, H. / Heboid, G. -- Limb Malformations Induced in the Rat by Amniotic Puncture / Houben, Jean-Jacques -- The Effect of Sodium Salicylate on Limb Development / Beck, F. / Gulamhusein, A.P. -- a,a'-Dipyridyl Teratogenicity in the Rat / Lilja, S. -- D. Limb Defects in Man -- Approaches to Classification of Limb Defects / Lenz, W. -- Formal Genesis of Syndactyly / Lösch, G.M. -- Thalidomide and the Neural Crest / McCredie, Janet -- List of Participants -- Indexweiterlesen