Ozone is certainly effective, safe, with a benefit/ risk relationship like any other therapeutical concept, and not expensive. Nevertheless, it has raised the following questions; -Which mechanism of action does justify the therapeutical effectiveness of medical ozone? -How is it possible that a specific therapeutical concept is effective in so many diseases? -How can the clinical use be explained if the ozone is a powerful oxidant? The concept of ozone oxidative pre/post-conditioning as a mechanism of action of medical ozone is demonstrated for the first time by León et al. 1998. This mechanism, experimentally and clinically evidenced in this book, answers the previously stated questions.weiterlesen