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Poly(ADP-Ribose) Polymerase

Methods and Protocols

Produktform: E-Buch Text Elektronisches Buch in proprietärem

This detailed volume explores poly(ADP-ribose) polymerases (PARPs) in the biology of eukaryotes and their relevance to human health. Beginning with a section on the detection and quantification of poly(ADP-ribose) polymer (pADPr), the book continues by delving into the identification of protein targets, functional analysis, the poly(ADP-ribosyl)ating pathway in chromatin and genes expression, as well as the use of animal models and PARP1 inhibitor design and testing, and more. Written for the highly successful series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, presents essential new and classical methods for studying the pADPr-pathway.weiterlesen

Dieser Artikel gehört zu den folgenden Serien

Elektronisches Format: PDF

Sprache(n): Englisch

ISBN: 978-1-07-162891-1 / 978-1071628911 / 9781071628911

Verlag: Springer US

Erscheinungsdatum: 14.12.2022

Seiten: 446

Auflage: 3

Herausgegeben von Alexei V. Tulin

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