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Sepsis

Methods and Protocols

Produktform: Buch / Einband - fest (Hardcover)

This detailed volume presents a variety of animal models that are commonly used to study sepsis and some key procedures to measure specific disease outcomes. The chapters describe well-established surgical and nonsurgical rodent models of sepsis, presented by experts in the field. In addition, the book includes protocols for burn injury and sepsis, modeling the mouse intensive care unit (MICU), and the development of humanized mice, which may be useful tools to increase the translational potential of rodent sepsis research. There is a chapter discussing the use of biomarkers for sepsis diagnosis and prognosis in humans and mice, as well as chapters describing specific methods for biomarker measurement, and the use of analgesics and humane endpoints in rodent sepsis research. Finally, agent-based computational modeling is presented as a valuable complementary approach to study sepsis. Written for the highly successful series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, serves as an ideal guide for researchers working toward improving the identification and treatment of septic patients.weiterlesen

Dieser Artikel gehört zu den folgenden Serien

Sprache(n): Englisch

ISBN: 978-1-07-161487-7 / 978-1071614877 / 9781071614877

Verlag: Springer US

Erscheinungsdatum: 29.05.2021

Seiten: 262

Auflage: 1

Herausgegeben von Wendy E. Walker

235,39 € inkl. MwSt.
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lieferbar - Lieferzeit 10-15 Werktage

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