This book discusses unique ion channels and transporters that are located within epithelial tissues ofvarious organs including the kidney, intestine, pancreas and respiratory tract. The authors will show, that each of these channels and transporters play crucial roles in transepithelial ion and fluid transport across all epithelia and their responsibility in maintaining homeostasis. The reader gains an understanding of the fundamentals of ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. All three volumes will thus highlight the importance of ion channels and transporters in basic physiology and pathophysiology of human diseases.The focus of the third volume lies with the different major ion channel and transporter families. Additionally, this volume benefits from many pharmaceutical contributors and their insights into recent pre-clinical drug discovery efforts and results from clinical trials. Overall, these chapters offer a more thorough coverage of individual ion channels and transporters from the 1st Edition. That makes it an insightful contribution for physiology students, scientists and clinicians.weiterlesen