A detailed look at the Ccl2/Cx3cr1 mouse model of AMD follows. Then a detailed examination of the systemic changes in AMD is followed by a discussion of  cerium oxide nanoparticle reduction of oxidative stress.  Two chapters discuss progenitor cells in the cause and treatment of retinal diseases including AMD and diabetic retinopathy. Natural compounds in the prevention and treatment of retinal diseases are exhaustively presented, followed by a chapter on serotonin 5-HT receptor agonists in oxidative stress of the retina. The current anti-VEGF treatment strategies of neovascular AMD are then given. The volume continues with a detailed look at nitric oxide and inducible nitric oxide synthase in retinal vascular disease, an explanation of an technique of studying the effect of lipid hydroperoxides on circulating leucocytes in the retina, an excellent review of oxidative stress in retinopathy of  prematurity, and a look at VEGF induced oxidative stress in the retinal ganglion cell.  The book ends with a detail examination of the role of carotenoids in retinal health and disease. These 31 chapters summarize what is known about oxidative stress in retinal and choroidal disorders. All those involved with degenerative diseases of the eye will find to be illuminating and comprehensive.weiterlesen