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Trinucleotide Repeats

Methods and Protocols

Produktform: Buch / Einband - fest (Hardcover)

This detailed book contains techniques to explore the unusual properties of the peculiar microsatellites known as trinucleotide repeats.  Beginning with technical challenges raised by secondary structure-forming repeats and their propensity to contract and expand over time, the book continues with genetic screens in , experimental systems to study trinucleotide repeat instability in human cells, dedicated experimental systems in appropriate cell types, as well as gene therapy approaches using the CRISPR-Cas family of endonucleases.  Written for the highly successful series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, serves as a valuable aid to experts and newcomers alike who seek to investigate this fascinating and ever-expanding field of study.weiterlesen

Dieser Artikel gehört zu den folgenden Serien

Sprache(n): Englisch

ISBN: 978-1-4939-9783-1 / 978-1493997831 / 9781493997831

Verlag: Springer US

Erscheinungsdatum: 05.10.2019

Seiten: 286

Auflage: 1

Herausgegeben von Guy-Franck Richard

160,49 € inkl. MwSt.
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