The study of rare lung disorders enhances our understanding of common pulmonary diseases such as fibrosis and emphysema. Molecular Basis of Lung Disease: Insights from Rare Disorders brings together a panel of distinguished clinicians and molecular scientists who are experts in a range of rare lung diseases and their underlying molecular defects. Each chapter focuses on the pathogenic mechanisms and therapeutic targets suggested by basic research and follows an easy to read format: brief introduction followed by discussion of epidemiology, genetic basis and molecular pathogenesis, animal models, clinical presentation, diagnostic approaches, conventional management and treatment strategies, as well as future therapeutic targets and directions. Disorders ranging from the Marfan and Goodpasture’s syndromes to Sarcoidosis and alpha one titrypsin deficiency are treated in detail. Written for pulmonary clinicians and scientists alike, Molecular Basis of Lung Disease: Insights from Rare Disorders is a comprehensive and invaluable nesource that sheds new light on the molecular mechanisms influencing the clinical presentation and treatment strategies for these debilitating disorders.

This book offers a clear approach to the different sleep disorders, with a major focus on respiratory disorders of sleep. It provides a concise, evidence-based review of sleep medicine for the pulmonologist and other health professionals.

The first thorough reference on the topic, this book covers the profound impact of obesity on the pathology of common pulmonary diseases. Discussion includes airway inflammation, sleep apnea, asthma, pulmonary hypertension, obesity hypoventilation and more.

This state-of-the art review of interventional bronchoscopy procedures covers the scientific basis of each, plus indications, techniques, results, complications and costs. Discusses advantages of new techniques and when to choose new over existing techniques.

This state-of-the art review of interventional bronchoscopy procedures covers the scientific basis of each, plus indications, techniques, results, complications and costs. Discusses advantages of new techniques and when to choose new over existing techniques.